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LEVULAN KERASTICK and BLU-U Photodynamic Therapy

Levulan® Kerastick® (aminolevulinic acid HCl) for Topical Solution, 20% and BLU-U® Blue Light Photodynamic Therapy is a powerful, patented, versatile technology platform. When delivered to target tissues, LEVULAN KERASTICK is taken up and converted by fast growing cells into propoporphyrin IX (PpIX), a potent photosensitizer which is then activated by the BLU-U.

Part 1: Generation of photosensitizer

  • Application of prodrug – LEVULAN KERASTICK
  • Accumulation of endogenous photosensitizer - ALA

Part 2: Activation of photosensitizer

  • Application of light – BLU-U blue light
  • Presence of O2
  • Generation of Reactive O2 Species (ROS) ... leading to cell death


                    Part 1                                                                          Part 2






DUSA cautions that the information contained on this site is intended for informational purposes only and should not be interpreted as medical advice. Please consult your healthcare provider with any questions you may have.



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